The role of CURIOSIN® (zinc hyaluronan) in modern wound management encompasses:
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providing moist wound environment, the primary objective of wound management - hyaluronan* is the most hydrated biomolecule known (1 g hyaluronan can associate with up to 10000 times of its own mass of water) and the only one retaining 30% water even upon drying. Zinc hyaluronan has a stronger water-binding effect compared to hyaluronan.
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promoting physiological wound healing - once applied, zinc hyaluronan forms a molecular continuum with the hyaluronan fragments of the damaged skin restoring the microchannels for the diffusion of water and passage of metabolic and signal molecules - providing the optimal micro-environment for wound healing to start (see "How CURIOSIN® works?").
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in addition, zinc hyaluronan may reduce scar formation and restore healthy skin conditions via helping the damaged skin to heal from the depth of the wound to the skin surface
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infection control - the hydrated zinc hyaluronan layer acts as an antimicrobial filter preventing microrganisms from the environment (airborne or contact origin) from reaching the wound surface.
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pain control - via scavenging tissue damaging factors such as free radicals, zinc hyaluronan helps in reducing tissue inflammation resulting in less wound pain.
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ease-of-use - CURIOSIN® is an easy to apply, clear, transparent, odourless, non-irritant preparation supplied as Gel and Fluid in portable multidose containers. It forms an elastic, unvisible film on the wound surface providing a protective layer shielding the wound, allowing to follow the healing procedure. Superficial wounds need no covering.
*hyaluronan is a term encompassing the names used for the different forms the molecule can take, such as: hyaluronic acid, hyaluronate, sodium hyaluronate, hyaluronic acid sodium salt, HA, NaHA etc.
Further information, useful links for the topic:
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